Ziprasidone hydrochloride

CAS No. 122883-93-6

Ziprasidone hydrochloride ( CP88059 hydrochloride;CP 88059 hydrochloride )

Catalog No. M10892 CAS No. 122883-93-6

A full antagonist of D2 and 5-HT2A receptors with Ki of 6.8 and 0.6 nM, respectively; also is a partial agonist of 5-HT1A, and a partial antagonist of 5-HT2C and 5-HT1D receptors.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
10MG 45 In Stock
25MG 77 In Stock
50MG 122 In Stock
100MG 152 In Stock
200MG Get Quote In Stock
500MG Get Quote In Stock
1G Get Quote In Stock

Biological Information

  • Product Name
    Ziprasidone hydrochloride
  • Note
    Research use only, not for human use.
  • Brief Description
    A full antagonist of D2 and 5-HT2A receptors with Ki of 6.8 and 0.6 nM, respectively; also is a partial agonist of 5-HT1A, and a partial antagonist of 5-HT2C and 5-HT1D receptors.
  • Description
    A full antagonist of D2 and 5-HT2A receptors with Ki of 6.8 and 0.6 nM, respectively; also is a partial agonist of 5-HT1A, and a partial antagonist of 5-HT2C and 5-HT1D receptors; exhibits potent antipsychotic activity in vivo.Schizophrenia Approved
  • Synonyms
    CP88059 hydrochloride;CP 88059 hydrochloride
  • Pathway
    Endocrinology/Hormones
  • Target
    5-HT Receptor
  • Recptor
    5-HTtransporter;5-HT1A;5-HT1B;5-HT1D;5-HT2A;5-HT2C;5-HT6;5-HT7;D1;D2;D3;H1receptor;norepinephrinetransporter(NET);α1A-adrenergicreceptor;α2A-adrenergicreceptor
  • Research Area
    Neurological Disease
  • Indication
    Schizophrenia

Chemical Information

  • CAS Number
    122883-93-6
  • Formula Weight
    449.40
  • Molecular Formula
    C21H22Cl2N4OS
  • Purity
    >98% (HPLC)
  • Solubility
    10 mM in DMSO
  • SMILES
    Cl.ClC1=C(CCN2CCN(CC2)C2=NSC3=CC=CC=C23)C=C2CC(=O)NC2=C1
  • Chemical Name
    2H-Indol-2-one, 5-[2-[4-(1,2-benzisothiazol-3-yl)-1-piperazinyl]ethyl]-6-chloro-1,3-dihydro-, hydrochloride (1:1)

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Mattei C, et al. J Cent Nerv Syst Dis. 2011 Feb 15;3:1-16.
2. Seeger TF, et al. J Pharmacol Exp Ther. 1995 Oct;275(1):101-13.
3. Schotte A, et al. Psychopharmacology (Berl). 1996 Mar;124(1-2):57-73.
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